I am happy to announce the publication of a research article from my PhD, entitled: "Mechanical and Microstructural Properties of Additively Manufactured Porous Titanium Alloy Constructs for Orthopaedic and Maxillofacial Reconstruction" in the journal Biomedical Engineering Advances, an Elsevier publication.
📖 The pre-proof version of this open access article can be seen here.
🔍 Study Overview:
Our research investigates the mechanical and microstructural properties of porous Ti6Al4V constructs fabricated via Selective Laser Melting (SLM) for mandibular reconstruction and orthopedic applications. We examined how porosity, surface roughness, and internal defects influence mechanical strength, stiffness, and fatigue performance. Additionally, finite element analysis (FEA) models were developed to accurately predict the mechanical behavior of these constructs under physiological loading conditions.
💡 Key Findings:
✅ Surface roughness and internal porosity impact mechanical performance, with internal defects comprising <1.0% of total volume.
✅ FEA models predicted tensile and flexural properties with deviations <11%, confirming their reliability in implant design.
✅ Optimal strut thickness (350-450 µm) was identified, yielding mechanical properties closely matching those of the human mandible.
🚀 Implications:
This study underscores the clinical potential of patient-specific, porous titanium implants by demonstrating the feasibility of rapid FEA-based design and validation. Our findings pave the way for improved osseointegration, vascularization, and long-term implant durability, enhancing outcomes in maxillofacial and orthopedic reconstruction.
👨🔬 Researchers involved in this article 👩🔬
This research was conducted under the supervision of Dr. Amin Rizkalla at Western University and co-authored by a multidisciplinary team of researchers affiliated with Faculty of Engineering at Western University, Schulich School of Medicine & Dentistry, Robarts Research Institute, and Western University's Bone and Joint Institute. The co-authors of this article are:
📖 The pre-proof version of this open access article can be seen here.
🔍 Study Overview:
Our research investigates the mechanical and microstructural properties of porous Ti6Al4V constructs fabricated via Selective Laser Melting (SLM) for mandibular reconstruction and orthopedic applications. We examined how porosity, surface roughness, and internal defects influence mechanical strength, stiffness, and fatigue performance. Additionally, finite element analysis (FEA) models were developed to accurately predict the mechanical behavior of these constructs under physiological loading conditions.
💡 Key Findings:
✅ Surface roughness and internal porosity impact mechanical performance, with internal defects comprising <1.0% of total volume.
✅ FEA models predicted tensile and flexural properties with deviations <11%, confirming their reliability in implant design.
✅ Optimal strut thickness (350-450 µm) was identified, yielding mechanical properties closely matching those of the human mandible.
🚀 Implications:
This study underscores the clinical potential of patient-specific, porous titanium implants by demonstrating the feasibility of rapid FEA-based design and validation. Our findings pave the way for improved osseointegration, vascularization, and long-term implant durability, enhancing outcomes in maxillofacial and orthopedic reconstruction.
👨🔬 Researchers involved in this article 👩🔬
This research was conducted under the supervision of Dr. Amin Rizkalla at Western University and co-authored by a multidisciplinary team of researchers affiliated with Faculty of Engineering at Western University, Schulich School of Medicine & Dentistry, Robarts Research Institute, and Western University's Bone and Joint Institute. The co-authors of this article are:
- Dr. Haojie Mao
- Dr. David Holdsworth
- Dr. S. Jeffrey Dixon
We are excited about the potential applications of this work in personalized medicine and implant design. Looking forward to discussions and collaborations on this topic! 🚀
This article is the second paper in the series of articles related to my PhD, with three of the papers now published. Feel free to visit my website for further information regarding this research and associated publications: https://lnkd.in/giPueUmk
This article is the second paper in the series of articles related to my PhD, with three of the papers now published. Feel free to visit my website for further information regarding this research and associated publications: https://lnkd.in/giPueUmk